CBR1 Polyclonal Antibody | E-AB-10951

CBR1 Polyclonal Antibody | E-AB-10951 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: 15 hydroxyprostaglandin dehydrogenase [NADP+], 15-hydroxyprostaglandin dehydrogenase [NADP+], Carbonyl reductase [NADPH] 1, Carbonyl Reductase 1, CBR 1, CBR1, CBR1, CRN, NADPH dependent carbonyl reductase 1, NADPH-dependent carbonyl reductase 1, Prostaglandin 9 ketoreductase, Prostaglandin 9-ketoreductase, Prostaglandin E(2) 9 reductase, Prostaglandin-E(2) 9-reductase, SDR21C1

Application: WB, IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cell Biology, Metabolism, Signal Transduction

Background: Carbonyl reductase is one of several monomeric, NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds. This enzyme is widely distributed in human tissues. Another carbonyl reductase gene, CRB3, lies close to this gene on chromosome 21q. NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol.

Concentration: 0.3 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human CBR1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:1000-1:5000, IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 30 kDa

Molecular Weight(Observed): N/A