CBS Polyclonal Antibody | E-AB-14671

CBS Polyclonal Antibody | E-AB-14671 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: AI047524, AI303044, Beta thionase, Beta-thionase, Cbs, Cbs cystathionine beta-synthase, CBS, Cystathionine beta synthase, Cystathionine beta-synthase, EC 4.2.1.22, HIP 4, HIP4, Methylcysteine synthase, MGC18856, MGC18895, MGC37300, OTTHUMP00000109416, OTTHUMP00000109418, Serine sulfhydrase

Application: WB, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Metabolism, Signal Transduction

Background: The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. Multiple alternatively spliced transcript variants have been found for this gene.

Concentration: 0.2 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human CBS

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:200-1:1000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 61 kDa

Molecular Weight(Observed): N/A