CBX5 Antibody | 13-877

CBX5 Antibody | 13-877 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-191 of human CBX5 (NP_001120794.1) .

Research Area: Other

Tested Application: WB, IF, IP, ChIP

Application: WB: 1:500 - 1:2000
IF: 1:50 - 1:200
IP: 1:50 - 1:200
ChIP: 1:20 - 1:100

Specificiy: N/A

Positive Control 1: HeLa

Positive Control 2: K-562

Positive Control 3: SW620

Positive Control 4: A-673

Positive Control 5: SH-SY5Y

Positive Control 6: N/A

Molecular Weight: Observed: 22kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: CBX5, HP1, HP1A, HEL25

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified.