CBX7 Antibody (C-term) [APR33010G]

CBX7 Antibody (C-term) [APR33010G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This CBX7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 168-201 amino acids from the C-terminal region of human CBX7.

Cellular Localisation: Nucleus

Molecular Weight: 28341

Clone: Polyclonal

Gene Name: CBX7

Gene ID: 23492

Function: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3) . Binds to trimethylated lysine residues in histones, and possibly also other proteins. Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity.

Summary: N/A

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000 WB--1:500

Synonyms: Chromobox protein homolog 7, CBX7