CCDC125 Polyclonal Antibody | BS65968

CCDC125 Polyclonal Antibody | BS65968 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat,Pig,Cow,Sheep,

Application: WB,

Application Range: WB=1:500-2000

Background: CCDC125, also known as KENAE, is a 511 amino acid protein expressed as two isoforms produced by alternative splicing and encoded by a gene mapping to human chromosome 5. With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6% of human genomic DNA. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CCDC125 Polyclonal Antibody detects endogenous levels of CCDC125 protein.

Molecular Weight: 52 kD

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: CC125_HUMAN; CCDC125; Coiled-coil domain-containing protein 125; KENAE;y Protein kenae.

Immunogen: KLH conjugated synthetic peptide derived from human CCDC125:151-250/511

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: affinity purified by Protein A

Pathway: