CCDC3 Antibody (C-term) [APR32597G]

CCDC3 Antibody (C-term) [APR32597G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This CCDC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-222 amino acids from the C-terminal region of human CCDC3.

Cellular Localisation: Secreted {ECO:0000250|UniProtKB:Q9D6Y1}.

Molecular Weight: 30731

Clone: Polyclonal

Gene Name: CCDC3

Gene ID: 83643

Function: Negatively regulates TNF-alpha-induced pro-inflammatory response in endothelial cells (ECs) via inhibition of TNF-alpha-induced NF-kappaB activation in ECs (PubMed:25193116) . Positively regulates lipid accumulation in adipose cells (By similarity) .

Summary: Tissue Location: Expressed in umbilical vein endothelial cells (HUVEC), and at lower levels in aortic smooth muscle cells (HASMC)

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, IHC-P, FC

Dilution: WB--1:1000 IHC-P--1:100~500 FC--1:10~50

Synonyms: Coiled-coil domain-containing protein 3, Fat/vessel-derived secretory protein, Favine, CCDC3