CCDC88A Polyclonal Antibody | E-AB-13059

CCDC88A Polyclonal Antibody | E-AB-13059 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: AKT iphosphorylation enhancer, Akt phosphorylation enhancer, APE, Ccdc88a, Coiled coil domain containing 88A, Coiled coil domain containing protein 88A, Coiled-coil domain-containing protein 88A, FLJ10392, G alpha interacting vesicle associated protein, G alpha-interacting vesicle-associated protein, Galpha interacting vesicle associated protein, Girders of actin filament, Girdin, GIV, GRDN, GRDN, HkRP1, Hook related protein 1, Hook-related protein 1, KIAA1212

Application: IHC, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Neuroscience, Signal Transduction

Background: This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human CCDC88A

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A