CCL2 Antibody | 7201

CCL2 Antibody | 7201 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: Predicted species reactivity based on immunogen sequence: Pig: (81%) , Horse: (81%) , Bovine: (75%) , Rabbit: (75%) , Guinea pig: (90%)

Immunogen: Rabbit polyclonal CCL2 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human CCL2.
The immunogen is located within the last 50 amino acids of CCL2.

Research Area: Immunology

Tested Application: E, WB, IHC-P, IF

Application: CCL2 antibody can be used for detection of CCL2 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Specificiy: N/A

Positive Control 1: Cat. No. 1204 - K562 Cell Lysate

Positive Control 2: Cat. No. 10-901 - Human Spleen Tissue Slide

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 11 kDa
Observed: 14 kDa

Validation: N/A

Isoform: N/A

Purification: CCL2 Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: CCL2 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: CCL2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: CCL2 Antibody: HC11, MCAF, MCP1, MCP-1, SCYA2, GDCF-2, SMC-CF, HSMCR30, C-C motif chemokine 2, HC11

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: CCL2 Antibody: CCL2, also known as monocyte chemotactic protein 1 (MCP1) , belongs to the intercrine beta (chemokine CC) family. It is produced by a variety of cell types and is a potent chemoattractant for monocytes, memory T lymphocytes, and natural killer (NK) cells. It is upregulated during infection and inflammation. CCL2 is a potent basophil activator but does not affect eosinophils, whereas the related protein MCP2 stimulates both eosinophils and basophils. MCP3 has been shown to have the broadest range of influence. CCL2 has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis.