CCL24 (Human) ELISA Kit | E5119-100

CCL24 (Human) ELISA Kit | E5119-100

Description: CCL24 is a small cytokine belonging to the CC chemokine family which is also known as myeloid progenitor inhibitory factor 2 (MPIF-2) or eosinophil chemotactic protein 2 (eotaxin-2). CCL24 interacts with chemokine receptor CCR3 to induce chemotaxis in eosinophils. It is chemotactic for resting T-lymphocytes, and eosinophils and has a lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. Elevated levels of CCL24 have been seen in patients with aspirin-exacerbated respiratory disease, such as asthma. CCL24 plays an important role in pathological processes of skin and lung inflammation and fibrosis. Inhibition of CCL24 by CM-101 mAb can be potentially beneficial for therapeutic use in systemic sclerosis patients. CCL24 contribute to the biology of cancer by M2 macrophage polarization, angiogenesis, invasion and migration, and recruitment of eosinophils. CCL24 can be used as a potential biomarker in several cancers including colon cancer, non-small cell cancer, and nasopharyngeal carcinoma as the plasma level of CCL24 is increased. ’s CCL24 (Human) ELISA Kit is used for the quantitative detection of CCL24 in serum, plasma, tissue homogenates and other biological fluids. It is based on the principle of sandwich ELISA. The capture antibody is pre-coated on 96-well plates. The standards, test samples and biotin conjugated detection antibody are added to the wells subsequently, and washed with wash buffer. HRP-Streptavidin is added and unbound conjugates are washed away with wash buffer. The HRP enzymatic reaction is detected using TMB-substrate. Finally, an acidic stop solution terminates the enzymatic reaction. The color developed is directly proportional to the amount of CCL24 in the sample.

Alternate Name: CCL24 ELISA Kit; MPIF2 ELISA Kit; Eotaxin-2 ELISA Kit; SCYA24 ELISA Kit; Ckb-6 ELISA Kit

Tag Line: A highly sensitive sandwich ELISA kit for the quantitative measument of CCL24

Summary: N/A

Detection Method: Absorbance is measured at 450 nm

Sample Type: Human Serum, Plasma, Tissue lysates and other biological fluids

Species Reactivity: Human

Applications: The ELISA kit is used for the quantitative detection of CCL24 in serum, plasma, tissue homogenates and other biological fluids

Features & Benefits: Assay Precision; Intra-Assay CV < 8% and Inter-Assay < 10% Sensitivity: 9.375 pg/ml Detection range: 15.625-1000 pg/ml Recovery Rate: 85-99% for serum, 86-94% for EDTA plasma and 93-103% for heparin plasma Highly sensitive and specific