CCR3 Antibody (Center) [APR15304G]

CCR3 Antibody (Center) [APR15304G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This CCR3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 291-318 amino acids from the Central region of human CCR3.

Cellular Localisation: Cell membrane; Multi-pass membrane protein

Molecular Weight: 41044

Clone: Polyclonal

Gene Name: CCR3

Gene ID: 1232

Function: Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES (CCL5) and CCL15 (PubMed:7622448, PubMed:8642344, PubMed:8676064) . Subsequently transduces a signal by increasing the intracellular calcium ions level (PubMed:8676064) . In addition acts as a possible functional receptor for NARS1 (PubMed:30171954) .

Summary: Tissue Location: In eosinophils as well as trace amounts in neutrophils and monocytes.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, FC

Dilution: WB--1:1000 FC--1:10~50

Synonyms: C-C chemokine receptor type 3, C-C CKR-3, CC-CKR-3, CCR-3, CCR3, CKR3, Eosinophil eotaxin receptor, CD193, CCR3, CMKBR3