CCR7 Antibody | 7649

CCR7 Antibody | 7649 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Homology: N/A

Immunogen: CCR7 antibody was raised against a 15 amino acid peptide near the center of human CCR7.
The immunogen is located within amino acids 180 - 230 of CCR7.

Research Area: Chemokines & Cytokines

Tested Application: E, WB, IHC-P, IF

Application: CCR7 antibody can be used for detection of CCR7 by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Specificiy: CCR7 antibody is human specific. CCR7 antibody is predicted to not cross-react with other CCR proteins.

Positive Control 1: Cat. No. 1306 - Human Spleen Tissue Lysate

Positive Control 2: Cat. No. 10-901 - Human Spleen Tissue Slide

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 42 kDa
Observed: 42 kDa

Validation: N/A

Isoform: N/A

Purification: CCR7 antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: CCR7 antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: CCR7 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: CCR7 Antibody: BLR2, EBI1, CD197, CDw197, CMKBR7, EVI1, C-C chemokine receptor type 7, BLR2, C-C CKR-7

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The CCR7 protein is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV) , and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation (1, 2) . The chemokine (C-C motif) ligand 19 (CCL19) has been reported to be a specific ligand of this receptor (3) .