CCT2 Antibody | 22-302

CCT2 Antibody | 22-302 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 206-535 of human CCT2 (NP_006422.1) .

Research Area: Cell Cycle, Signal Transduction

Tested Application: WB, IF, IP

Application: WB: 1:500 - 1:2000
IF: 1:50 - 1:200
IP: 1:50 - 1:100

Specificiy: N/A

Positive Control 1: MCF7

Positive Control 2: SKOV3

Positive Control 3: A-549

Positive Control 4: HT-29

Positive Control 5: Mouse spleen

Positive Control 6: Mouse ovary

Molecular Weight: Observed: 57kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: CCT2, 99D8.1, CCT-beta, CCTB, PRO1633, TCP-1-beta, TCP1 Beta

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT) , also known as the TCP1 ring complex (TRiC) . This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Two transcript variants encoding different isoforms have been found for this gene.