CD10 Antibody [2A1H5E1] | 32-127

CD10 Antibody [2A1H5E1] | 32-127 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human

Homology: N/A

Immunogen: Ni-NTA purified recombinant human CD-10 expressed in E. Coli strain BL21 (DE3) .

Research Area: Signal Transduction

Tested Application: E, IHC

Application: IHC (P) :Dilution 1:100 - 1:200
IHC (F) :Dilution 1:200 - 1:400
ELISA:Propose dilution 1:10, 000.
Determining optimal working dilutions by titration test.

Specificiy: N/A

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: Antibody is purified by protein G affinity chromatography.

Clonality: Monoclonal

Clone: 2A1H5E1

Isotype: IgG2b

Conjugate: Unconjugated

Physical State: N/A

Buffer: Purified antibody in PBS containing 0.03% sodium azide.

Concentration: N/A

Storage Condition: CD10 monoclonal antibody can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: EPN, Atriopeptidase, CALLA, NEP, SFE, CD10

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: CD10 is a 100 kDa glycoprotein, also designated Common Acute Lymphocytic Leukemia Antigen (CALLA) . It is a cell surface enzyme with neutral metalloendopeptidase activity which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt’s, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML) . It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue. CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells.