CD103 / ITGAE Antibody | A2300

ITGAE, also known as CD103, is an integrin that pairs with the beta 7 integrin to form the human mucosal lymphocyte-1 antigen. ITGAE is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL). It has a role in adhesion and may serve as an accessory molecule for IEL activation. ITGAE has been associated with diseases such as hairy cell leukemia and splenic marginal zone lymphoma. The presence of cytotoxic T cells positive for CD103 expression has been linked to prolonged survival in several malignancies, including gastric cancer, and is currently being explored as a prognostic biomarker as well as a potential therapeutic target.

A2300 | CD103 / ITGAE Antibody DataSheet

Antibody Target: Human CD103

Target Alternative Name: ITGAE Mucosal Lymphocyte 1 Antigen; HML-1 Antigen Integrin Subunit Alpha E HUMINAE

Tag Line: Integrin with a role in adhesion and a prognostic marker in certain cancer types

Category: GM-CSF

Host: Rabbit

Isotype: Rabbit IgG

Species Reactivities: Human Mouse Rat

Immunogen Sequence: Human CD103 peptide sequence (amino acids 19 to 200)

Accession #: P38570

Gene ID: 3682

Appearance: Liquid

Form: Rabbit polyclonal

Concentration:

Formulation: In PBS with 0.02% sodium azide, 50% glycerol, pH 7.3

Purification: Affinity purification

Application: Western Blotting

Positive Control:

Application And Usages:

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: TRUE

Immunocytochemistry Verified:

Immunofluorescence Verified: FALSE

Immunoprecipitation Verified: FALSE

FACS Verified:

ELISA Verified: FALSE

ChIP Verified: FALSE

Dot Blot Verified: FALSE

Flow Cytometry Verified: FALSE