CD105 Antibody [SN6] | 99-594

CD105 Antibody [SN6] | 99-594 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Horse

Homology: N/A

Immunogen: Antigen preparation isolated from cell membranes of leukemia cells derived from a patient with non-T/non-B-cell acute lymphoblastic leukemia (ALL)

Research Area: Cancer, Cell Cycle, Immunology, Signal Transduction

Tested Application: IHC-Fr, Flow, Blocking, IP, Neut, Depletion, Complement Mediated Cell Depletion

Application: CD105 Antibody [SN6] for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, immunoprecipitation, and purification assays.

Specificiy: CD105

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: N/A

Clonality: Monoclonal

Clone: [SN6]

Isotype: IgG1

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added

Concentration: 0.1 mg/mL

Storage Condition: Store vial at 2-8˚C

Alternate Name: Endoglin

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: CD105, also known as endoglin, is a 90 kDa type II transmembrane glycoprotein that is expressed on the cell surface as a disulfide-linked homodimer and is found on endothelial cells. CD105 is one of several receptors for the various isoforms of TGF��� which in turn is one of a family of proteins involved in regulation of cell differentiation, migration of cells, and control on the immune response.