Description
CD105 Antibody [SN6] (APC) | 99-597 | Gentaur UK, US & Europe Distribution
Host: Mouse
Reactivity: Human, Horse
Homology: N/A
Immunogen: Antigen preparation isolated from cell membranes of leukemia cells derived from a patient with non-T/non-B-cell acute lymphoblastic leukemia (ALL)
Research Area: Cancer, Cell Cycle, Immunology, Signal Transduction
Tested Application: Flow
Application: CD105 Antibody [SN6] for use in flow cytometry assays.
Specificiy: CD105
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: N/A
Clonality: Monoclonal
Clone: [SN6]
Isotype: IgG1
Conjugate: APC
Physical State: Liquid
Buffer: Supplied in PBS/NaN3 and a stabilizing agent
Concentration: Lot specific
Storage Condition: Store vial at 2-8˚C
Alternate Name: Endoglin
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: CD105, also known as endoglin, is a 90 kDa type II transmembrane glycoprotein that is expressed on the cell surface as a disulfide-linked homodimer and is found on endothelial cells. CD105 is one of several receptors for the various isoforms of TGF��� which in turn is one of a family of proteins involved in regulation of cell differentiation, migration of cells, and control on the immune response.