CD107a Antibody [1D4B] (APC) | 99-111

CD107a Antibody [1D4B] (APC) | 99-111 | Gentaur UK, US & Europe Distribution

Host: Rat

Reactivity: Mouse

Homology: N/A

Immunogen: Plasma membrane fraction of mouse embryo NIH/3T3 cell line

Research Area: Innate Immunity

Tested Application: IHC-Fr, ICC, Flow, Blocking, IP, Separation

Application: CD107a Antibody [1D4B] for use in flow cytometry assays.

Specificiy: CD107a

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: N/A

Clonality: Monoclonal

Clone: [1D4B]

Isotype: IgG2a

Conjugate: APC

Physical State: Liquid

Buffer: Supplied in PBS/NaN3 and a stabilizing agent

Concentration: 0.1 mg/mL

Storage Condition: Store vial at 2-8˚C

Alternate Name: LAMP-1, lysosomal-associated membrane protein 1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: CD107a, also known as lysosomal-associated membrane protein 1 (LAMP-1) , is a heavily glycosylated type I transmembrane protein that constitutes one of the two major sialoglycoproteins on lysosomal membranes that can be used to distinguish lysosomes from other organelles. It is a ligand for galaptin, an S-type lectin present in extracellular matrix, through its recognition of acetyllactosamine oligosaccharide chains and is a ligand for E-selectin-mediated cell adhesion. CD107a is principally expressed in epithelial cells and macrophages in a variety of organs in normal and beige mutant mice. It may function in protecting the inner surface of the lysosomal membrane by forming a barrier to lysosomal hydrolases.