CD109 Polyclonal Antibody | E-AB-40372

CD109 Polyclonal Antibody | E-AB-40372 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: 150 KDa TGF beta 1 binding protein, 150 KDa TGF-beta-1-binding protein, 7D1, 8A3, Activated T cell marker CD109, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7, CD 109, CD109, CD109 antigen, CD109, CPAMD7, DKFZp762L1111, E123, FLJ38569, FLJ41966, Gov system alloantigens on platelets, p180, Platelet specific Gov antigen, Platelet-specific Gov antigen, r150, RP11 525G3.1

Application: IHC

Reactivity: Human, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Immunology

Background: CD109, also named as CPAMD7, is a member of the alpha2-macroglobulin/complement superfamily. It is a glycosylphosphatidylinositol (GPI)-linked cell surface glycoprotein of approximately 170kd which is found on the cell surface of platelets, activated T-cells, and endothelial cells. CD109 binds to and negatively regulates signaling of transforming growth factor beta (TGF-beta). CD109 has been identified as part of the TGF-beta receptor system in human keratinocytes. Up regulation of CD109 expression has been observed in several different types of tumor. Multiple transcript variants encoding different isoforms have been found for CD109. The antibody can recognize all these 4 isoforms.

Concentration: 0.37 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant Human CD109 antigen protein

Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3

Purification Method: Antigen Affinity Purification

Dilution: IHC 1:100-1:300

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A