CD117 Antibody [ACK2] (PE-Cy7) | 76-900

CD117 Antibody [ACK2] (PE-Cy7) | 76-900 | Gentaur UK, US & Europe Distribution

Host: Rat

Reactivity: Mouse

Homology: N/A

Immunogen: N/A

Research Area: Cancer

Tested Application: Flow

Application: N/A

Specificiy: The ACK2 monoclonal antibody specifically reacts with mouse CD117 (c-Kit receptor) , a 145 kDa transmembrane tyrosine-kinase receptor encoded by the Kit gene.

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Clonality: Monoclonal

Clone: ACK2

Isotype: Rat IgG2b, kappa

Conjugate: PE-Cy7

Physical State: liquid

Buffer: Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Concentration: batch dependent

Storage Condition: The product should be stored undiluted at 4˚C and should be protected from prolonged exposure to light. Do not freeze.

Alternate Name: W, Bs, Fdc, Ssm, SCO1, SCO5, SOW3, CD117, c-KIT, Tr-kit, Gsfsco1, Gsfsco5, Gsfsow3, Kit

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The ACK2 monoclonal antibody specifically reacts with mouse CD117 (c-Kit receptor) , a 145 kDa transmembrane tyrosine-kinase receptor encoded by the Kit gene. The c-Kit receptor, also known as stem cell factor receptor, is expressed on hematopoietic progenitor cells in adult bone marrow, in progenitors of erythroid and myeloid lineages, and precursors of B and T cells. CD117 enhances the proliferation and the differentiation of the hematopoietic progenitor cells and seems to enhance the development of T cells, as the c-Kit receptor and its ligand are expressed by the thymus.