CD11a Antibody [38] | 99-340

CD11a Antibody [38] | 99-340 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human

Homology: N/A

Immunogen: Fibronectin purified monocytes

Research Area: Immunology, Signal Transduction

Tested Application: Flow

Application: CD11a Antibody [38] for use in flow cytometry, immunohistochemistry, immunoprecipitation, ELISA, blocking, and adhesion assays.

Specificiy: CD11a

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: N/A

Clonality: Monoclonal

Clone: [38]

Isotype: IgG2a

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added

Concentration: 0.1 mg/mL

Storage Condition: Store vial at 2-8˚C

Alternate Name: LFA-1alpha, integrin alphaL, ITGAL

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: CD11a, also known as leukocyte function-associated antigen-1 (LFA-1alpha) , represents the 180 kDa integrin alphaL subunit which combines with the CD18 beta2 integrin subunit to form the alphaLbeta2 integrin heterodimer. It is expressed on lymphocytes, granulocytes, monocytes, and macrophages and is upregulated on activated T cells. CD11a mediates adhesion of lymphocytes to vascular endothelium and is involved in costimulation.