CD11a polyclonal Antibody | BS90209

CD11a polyclonal Antibody | BS90209 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB ICC/IF IHC IP FC

Application Range: WB:1:1,000-1:5,000 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100

Background: Integrins are heterodimers composed of noncovalently associated transmembrane a and b subunits. The 16 a and 8 b subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, Collagen and Vitronectin. Certain integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: CD11a polyclonal Antibody detects endogenous levels of CD11a protein.

Molecular Weight: 180 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: LFA-1A, ITGAL, CD11A, Lymphocyte function associated antigen, type 1, alpha subunit, Antigen CD11A (p180), lymphocyte function associated antigen 1, alpha polypeptide, Antigen CD11A, CD 11a, CD11 antigen-like family member A, CD11a, CD11a antigen, Integrin Alpha L, Integrin alpha-L, Integrin gene promoter, Integrin, alpha L (antigen CD11A (p180), lymphocyte function associated antigen 1; alpha polypeptide), ITAL, Itgal, ITGAL protein, Leukocyte adhesion glycoprotein LFA 1 alpha chain, Leukocyte adhesion glycoprotein LFA-1 alpha chain, Leukocyte Adhesion Glycoprotein LFA1 Alpha Chain, Leukocyte function associated molecule 1 alpha chain, Leukocyte function-associated molecule 1 alpha chain, LFA 1 alpha (LFA1A), LFA 1 alpha, LFA 1, LFA 1A, LFA-1A, LFA1A, Ly15, Ly21, Lymphocyte function associated antigen 1, Lymphocyte Function Associated Antigen Type 1 alpha, lymphocyte function-associated antigen 1, alpha polypeptide, p180,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: Tumor-Infiltrating Immune Cell Marker Guide,