CD11b Antibody [ICRF44] (APC) | 99-465

CD11b Antibody [ICRF44] (APC) | 99-465 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Pig, Rhesus, Cynomolgus, Chimpanzee, Baboon

Homology: N/A

Immunogen: Rheumatoid synovial cells and human monocytes

Research Area: Immunology, Neuroscience, Signal Transduction

Tested Application: WB, ICC, Flow

Application: CD11b Antibody [ICRF44] for use in flow cytometry assays.

Specificiy: CD11b

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: N/A

Clonality: Monoclonal

Clone: [ICRF44]

Isotype: IgG1

Conjugate: APC

Physical State: Liquid

Buffer: Supplied in PBS/NaN3 and a stabilizing agent

Concentration: Lot specific

Storage Condition: Store vial at 2-8˚C

Alternate Name: Mac-1alpha, Mo-1, CR3, integrin alphaM, C3biR, ITGAM, CR3A, p170

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: CD11b is the 165 kDa alphaM chain which combines with the CD18 beta2 integrin subunit to form the Mac-1 heterodimer. It is expressed on activated lymphocytes, monocytes, granulocytes and a subset of NK cells. CD11b functions in cell-cell and cell-substrate interactions and is a ligand for C3bi, CD50 (ICAM-3) , CD54 (ICAM-1) and CD102 (ICAM-2) .