CD11c Antibody [3.9] | 99-467

CD11c Antibody [3.9] | 99-467 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Rhesus, Cynomolgus

Homology: N/A

Immunogen: Rheumatoid synovial cells and human monocytes

Research Area: Immunology, Signal Transduction

Tested Application: IHC-Fr, Flow, IP, Costimulation, Activity

Application: CD11c Antibody [3.9] for use in flow cytometry, immunohistochemistry, immunoprecipitation, and blocking assays.

Specificiy: CD11c

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: N/A

Clonality: Monoclonal

Clone: [3.9]

Isotype: IgG1

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added

Concentration: 0.1 mg/mL

Storage Condition: Store vial at 2-8˚C

Alternate Name: Integrin alphaX, Axb2, CR4, p150, 95

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: CD11c is a 150 kDa adhesion glycoprotein that associates with beta2 integrin to form the CD11c/CD18 heterodimer that binds CD54 (ICAM-1) and fibrinogen. It is expressed on NK cells, a subset of B and T cells, granulocytes, monocytes, and macrophages. It functions in cytotoxic T cell killing and in neutrophil and monocyte adhesion to endothelium.