CD154 Antibody [MR1] (FITC) | 76-868

CD154 Antibody [MR1] (FITC) | 76-868 | Gentaur UK, US & Europe Distribution

Host: Hamster

Reactivity: Mouse

Homology: N/A

Immunogen: N/A

Research Area: Immunology

Tested Application: Flow

Application: N/A

Specificiy: The MR1 monoclonal antibody specifically reacts with mouse CD154, a 39kDA transmembrane glycoprotein also known as CD40 ligand and gp39.

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Clonality: Monoclonal

Clone: MR1

Isotype: Armenian Hamster IgG

Conjugate: FITC

Physical State: liquid

Buffer: Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Concentration: batch dependent

Storage Condition: The product should be stored undiluted at 4˚C and should be protected from prolonged exposure to light. Do not freeze.

Alternate Name: IGM, IMD3, Ly62, TRAP, gp39, CD154, Cd40l, HIGM1, Ly-62, T-BAM, CD40-L, Tnfsf5, Cd40lg

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The MR1 monoclonal antibody specifically reacts with mouse CD154, a 39kDA transmembrane glycoprotein also known as CD40 ligand and gp39. CD154 is expressed on activated T cells and plays a role in B-T cell costimulation. The interaction of CD154 with CD40 induces B cell cycle entry and the signaling for T-dependent B cell activation. By interfering with this interaction, the MR1 antibody is reported to inhibit T and B lymphocyte activation.