CD164 Antibody (C-term) [APR04765G]

CD164 Antibody (C-term) [APR04765G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M, Rat

Specificity: This CD164 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 152-185 amino acids from the C-terminal region of human CD164.

Cellular Localisation: Lysosome membrane; Single-pass type I membrane protein Endosome membrane; Single-pass type I membrane protein. Cell membrane; Single-pass type I membrane protein

Molecular Weight: 20917

Clone: Polyclonal

Gene Name: CD164

Gene ID: 8763

Function: Sialomucin that may play a key role in hematopoiesis by facilitating the adhesion of CD34 (+) cells to the stroma and by negatively regulating CD34 (+) CD38 (lo/-) cell proliferation. Modulates the migration of umbilical cord blood CD133+ cells and this is mediated through the CXCL12/CXCR4 axis. May play an important role in prostate cancer metastasis and the infiltration of bone marrow by cancer cells. Promotes myogenesis by enhancing CXCR4-dependent cell motility. Positively regulates myoblast migration and promotes myoblast fusion into myotubes (By similarity) .

Summary: Tissue Location: Isoform 1 and isoform 3 are expressed in hematopoietic and non-hematopoietic tissues. Isoform 1 is expressed by prostate cancer tumors and prostate cancer cell lines. The expression is greater in bone metastases than in primary tumors. Expression in osseous metastasis is greater than that in soft tissue metastasis Isoform 2 is expressed in the small intestine, colon, lung, thyroid and in colorectal and pancreatic adenocarcinoma. Isoform 4 is expressed by both hematopoietic progenitor cells and bone marrow stromal cells

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Sialomucin core protein 24, MUC-24, Endolyn, Multi-glycosylated core protein 24, MGC-24, MGC-24v, CD164, CD164