CD18 Antibody [C71/16] | 98-652

CD18 Antibody [C71/16] | 98-652 | Gentaur UK, US & Europe Distribution

Host: Rat

Reactivity: Mouse

Homology: N/A

Immunogen: Cell membrane glycoproteins derived from mouse BW5147 T cell lymphoma cells

Research Area: Cancer

Tested Application: E, IHC-Fr, ICC, Flow, IP

Application: CD18 Antibody [C71/16] for use in flow cytometry, immunohistochemistry / immunocytochemistry, ELISA, western blotting, and immunoprecipitation assays.

Specificiy: CD18

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: N/A

Clonality: Monoclonal

Clone: [C71/16]

Isotype: IgG2a

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added

Concentration: 0.5 mg/mL

Storage Condition: Store vial at 2-8˚C

Alternate Name: Integrin beta2, ITGB2

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: CD18 represents the common beta2 integrin subunit that associates non-covalently with the alpha/beta chains of CD11a, CD11b, and CD11c to form various integrin heterodimers. It is expressed strongly on lymphocytes and monocytes and weakly on granulocytes. CD18 mediates a variety of heterotypic and homotypic intercellular adhesion reactions and it regulates the ligand-binding activates of the various CD11/CD18 complexes. The monoclonal antibody C71/16 has not been reported to inhibit cell adhesion.