CD19 Antibody [SJ25-C1] | 99-347

CD19 Antibody [SJ25-C1] | 99-347 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human

Homology: N/A

Immunogen: NALM-1 and NALM-16 leukemia cell line

Research Area: Cancer, Immunology, Signal Transduction

Tested Application: WB, WB-NR, Flow

Application: CD19 Antibody [SJ25-C1] for use in flow cytometry, immunohistochemistry, immunoprecipitation, and blocking assays.

Specificiy: CD19

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: N/A

Clonality: Monoclonal

Clone: [SJ25-C1]

Isotype: IgG1

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added

Concentration: 0.1 mg/mL

Storage Condition: Store vial at 2-8˚C

Alternate Name: B4, B-lymphocyte antigen, Leu-12

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: CD19 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily. It is expressed at all stages of B cell differentiation except terminally differentiated plasma cells. It is also present on the cell surface of follicular dendritic cells. CD19 associates with CD21, CD81, Leu 13 and/or MHC Class II molecules to form a signal transduction complex on the B cell surface. This signaling complex modulates the activation threshold for the B cell antigen receptor (BCR) .