Description
CD19 Antibody [SJ25-C1] (APC-Cy5.5) | 99-358 | Gentaur UK, US & Europe Distribution
Host: Mouse
Reactivity: Human
Homology: N/A
Immunogen: NALM-1 and NALM-16 leukemia cell line
Research Area: Cancer, Immunology, Signal Transduction
Tested Application: Flow
Application: CD19 Antibody [SJ25-C1] for use in flow cytometry assays.
Specificiy: CD19
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: N/A
Clonality: Monoclonal
Clone: [SJ25-C1]
Isotype: IgG1
Conjugate: APC-Cy5.5
Physical State: Liquid
Buffer: Supplied in PBS/NaN3 and a stabilizing agent
Concentration: Lot specific
Storage Condition: Store vial at 2-8˚C
Alternate Name: B4, B-lymphocyte antigen, Leu-12
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: CD19 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily. It is expressed at all stages of B cell differentiation except terminally differentiated plasma cells. It is also present on the cell surface of follicular dendritic cells. CD19 associates with CD21, CD81, Leu 13 and/or MHC Class II molecules to form a signal transduction complex on the B cell surface. This signaling complex modulates the activation threshold for the B cell antigen receptor (BCR) .