CD19 polyclonal Antibody | BS90222

CD19 polyclonal Antibody | BS90222 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB ICC/IF IHC

Application Range: WB:1:1,000-1:2,000 ICC:1:50-1:200 IHC:1:50-1:200

Background: CD19 is a transmembrane glycoprotein that contains two extracellular immunoglobulin-like domains. CD19 is selectively expressed on the cell surface of B-lymphocytes, where it activates intracellular signaling cascades involving both Ras and phosphatidylinositol 3-kinase pathways. Activation of CD19 results in cross-linking of the membrane protein immunoglobulin chains and the subsequent association with Src family protein tyrosine kinases (PTK) . Expression of CD19 is continuous throughout B-cell development and through terminal differentiation of B-cells into plasma cells. CD19 forms functional complexes with B-lymphocyte surface proteins, including integrin b1, CD21 and CD81, which are involved in regulating B-cell development.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: CD19 polyclonal Antibody detects endogenous levels of CD19 protein.

Molecular Weight: 95 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: CD19, Antibody, deficiency due to defect in CD19, included, AW495831, B lymphocyte antigen CD19, B lymphocyte surface antigen B4, B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, B4, CD19, CD19 antigen, CD19 molecule, Cd19 protein, CD19, CVID3, Differentiation antigen CD19, Leu 12, Leu-12, Leu12, MGC109570, MGC12802, T-cell surface antigen Leu-12,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: