CD23 Antibody [T��1] (FITC) | 99-500

CD23 Antibody [T��1] (FITC) | 99-500 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human

Homology: N/A

Immunogen: Purified human tonsil lymphocytes

Research Area: Immunology, Stem Cell, Cancer, Cell Cycle

Tested Application: Flow, Separation

Application: CD23 Antibody [T��1] for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.

Specificiy: CD23

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: N/A

Clonality: Monoclonal

Clone: [T��1]

Isotype: IgG3

Conjugate: FITC

Physical State: Liquid

Buffer: Supplied in PBS/NaN3

Concentration: Lot specific

Storage Condition: Store vial at 2-8˚C

Alternate Name: FCepsilonRII, B6, Leu-20, BLAST-2, low affinity IgE receptor

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: CD23 is a 45 kDa type II integral membrane glycoprotein that is the low affinity receptor for IgE. It also binds to CD21 and the alpha chains of CD11b and CD11c. It is expressed by B cells and monocytes and, weakly, on T cells, follicular dendritic cells, eosinophils, NK cells, Langerhans cells, and platelets. It is upregulated in response to B cell activation, CD40 ligation, or in response to IL-4 or IL-13. CD23 is responsible for regulation of IgE synthesis and may play a role in antigen presentation by B cells and follicular dendritic cells by interacting with CD40.