CD24 Antibody (Center) [APR33502G]

CD24 Antibody (Center) [APR33502G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This CD24 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 17-38 amino acids from the Central region of human CD24.

Cellular Localisation: Cell membrane; Lipid-anchor, GPI-anchor.

Molecular Weight: 8083

Clone: Polyclonal

Gene Name: CD24

Gene ID: 100133941

Function: May have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin- like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells (PubMed:11313396) . In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90. Plays a role in the control of autoimmunity (By similarity) .

Summary: Tissue Location: B-cells. Expressed in a number of B-cell lines including P32/ISH and Namalwa. Expressed in erythroleukemia cell and small cell lung carcinoma cell lines. Also expressed on the surface of T-cells.

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000-1:2000

Synonyms: Signal transducer CD24, Small cell lung carcinoma cluster 4 antigen, CD24, CD24, CD24A