CD247, human recombinant | 7340

T-cell surface glycoprotein CD3 zeta chain, also known as CD247, belongs to the CD3Z/FCER1G family. CD247 is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Recombinant human CD247 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

7340 | CD247 human recombinant DataSheet

Biomolecule/Target: CD247

Synonyms: T-cell surface glycoprotein CD3 zeta chain, CD3-ZETA, CD3H, CD3Q, CD3Z, T3Z, TCRZ

Alternates names: T-cell surface glycoprotein CD3 zeta chain, CD3-ZETA, CD3H, CD3Q, CD3Z, T3Z, TCRZ

Taglines: Plays a role in coupling antigen recognition to several intracellular signal-transduction pathways

NCBI Gene ID #: 20305

NCBI Gene Symbol: CCL6

Gene Source: Human

Accession #: P27784

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 97%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: N/A

Activity (Specifications/test method): N/A

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 15.4 kDa (136 aa, 52-164 aa + His Tag), confirmed by MALDI-TOF.

Concentration: 0.5 mg/ml

Appearance: Liquid

Physical form description: 0.5 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 10% glycerol and 1 mM DTT.

Reconstitution Instructions: N/A

Amino acid sequence: MGSSHHHHHH SSGLVPRGSH MGSRVKFSRS ADAPAYQQGQ NQLYNELNLG RREEYDVLDK RRGRDPEMGG KPQRRKNPQE GLYNELQKDK MAEAYSEIGM KGERRRGKGH DGLYQGLSTA TKDTYDALHM QALPPR