CD25 Antibody [BC96] (PE) | 99-503

CD25 Antibody [BC96] (PE) | 99-503 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Rhesus, Cynomolgus

Homology: N/A

Immunogen: N/A

Research Area: Immunology

Tested Application: WB, IHC-P, IHC-Fr, Flow

Application: CD25 Antibody [BC96] for use in flow cytometry assays.

Specificiy: CD25

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: N/A

Clonality: Monoclonal

Clone: [BC96]

Isotype: IgG1

Conjugate: PE

Physical State: Liquid

Buffer: Supplied in PBS/NaN3 and a stabilizing agent

Concentration: Lot specific

Storage Condition: Store vial at 2-8˚C

Alternate Name: IL-2Ralpha, Tac antigen

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The BC96 monoclonal antibody reacts with human CD25, the 55 kDa interleukin-2 receptor alpha chain (IL-2Ralpha) . CD25 is expressed by early progenitors of T and B lineage as well as by activated mature T and B lymphocytes. By itself, CD25 binds IL-2 only with low affinity. However, CD25 associates with CD122 (IL-2 receptor beta chain) and CD132 (common gamma chain) to form the high affinity IL-2 receptor. CD25 plays a role in lymphocyte differentiating and activation/proliferation. CD25 is expressed on activated B cells, monocytes/macrophages, and T cells.