CD274, mouse recombinant | 7311

CD274, also known as programmed cell death 1 ligand 1(PDCD1L1), is involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. This protein interacts with PDCD1 inhibits T-cell proliferation and cytokine production. Recombinant mouse CD274 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

7311 | CD274 mouse recombinant DataSheet

Biomolecule/Target: CD274

Synonyms: CD274 antigen, A530045L16Rik, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1

Alternates names: CD274 antigen, A530045L16Rik, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1

Taglines: Involved in the costimulatory signal, essential for T-cell proliferation

NCBI Gene ID #: 796

NCBI Gene Symbol:

Gene Source: Mouse

Accession #: P01258

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 97%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: < 1.0 EU per 1 microgram of protein

Activity (Specifications/test method): N/A

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 27.6 kDa (246 aa, 19-239 aa + His tag), confirmed by MALDI-TOF.

Concentration: 1 mg/ml

Appearance: Liquid

Physical form description: 1 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl and 10% glycerol.

Reconstitution Instructions: N/A

Amino acid sequence: MGSSHHHHHH SSGLVPRGSH MGSHM RASLPKDQLL KGNAALQITD VKLQDAGVYC CIISYGGADY KRITLKVNAP YRKINQRISV DPATSEHELI CQAEGYPEAE VIWTNSDHQP FTITA PKDLYVVEYG SNVTMECRFP VERELDLLAL VVYWEKEDEQ VIQFVAGEED LKPQHSNFRG VSGKRSVTTS RTEGMLLNVT SSLRVNATAN DVFYCTFWRS QPGQNHTAEL IIPELPATHP PQNRTH