CD284 Monoclonal Antibody | E-AB-70229

CD284 Monoclonal Antibody | E-AB-70229 | Gentaur UK, US & Europe Distribution

Type: Monoclonal Antibody

Synonyms: ARMD10, CD284, CD284 antigen, Homolog of Drosophila toll, hToll, TLR 4, TLR4, TLR4, TOLL, Toll like receptor 4, Toll-like receptor 4

Application: IHC

Reactivity: Mouse, Rat

Host: Mouse

Isotype: IgG

Reserch Areas: Cancer, Cardiovascular, Immunology, Microbiology

Background: TLR4, also named as CD284, belongs to the Toll-like receptor family. TLR4 cooperates with LY96 and CD14 to mediates the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.

Concentration: 1.8 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein corresponding to Mouse TLR4

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Purification Method: Affinity purification

Dilution: IHC 1:200-1:800

Clone: 2E12C8

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A