CD31 Monoclonal Antibody | E-AB-70173

CD31 Monoclonal Antibody | E-AB-70173 | Gentaur UK, US & Europe Distribution

Type: Monoclonal Antibody

Synonyms: Adhesion molecule, CD31, CD31 antigen, CD31 EndoCAM, EndoCAM, FLJ34100, FLJ58394, GPIIA, GPIIA', PECA1, PECA1, Pecam 1, PECAM 1 CD31 EndoCAM, PECAM, PECAM-1, Pecam1, Platelet and endothelial cell adhesion molecule 1, Platelet endothelial cell adhesion molecule, Platelet/endothelial cell adhesion molecule 1

Application: IHC

Reactivity: Rat

Host: Mouse

Isotype: IgG

Reserch Areas: Cancer, Cardiovascular, Immunology, Signal Transduction, Stem Cells

Background: Platelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) is a member of the immunoglobulin gene superfamily of cell adhesion molecules. It is highly expressed on the surface of the endothelium, making up a large portion of its intracellular junctions. PECAM-1 is also present on the surface of hematopoietic cells and immune cells including platelets, monocytes, neutrophils, natural killer cells, megakaryocytes and some types of T-cell . As well as its role in cell-cell adhesion, PECAM-1 functions as a signaling receptor, and is involved in important physiological events such as nitric oxide production, regulation of T-cell immunity and tolerance, leukocyte transendothelial migration and inflammation and angiogenesis .

Concentration: 0.77 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse CD31

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Purification Method: Affinity purification

Dilution: IHC 1:200-1:500

Clone: 9A9A4

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A