CD35 Antibody [E11] | 99-511

CD35 Antibody [E11] | 99-511 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Rhesus, Cynomolgus, Chimpanzee, Baboon

Homology: N/A

Immunogen: Acute monocytic leukemia cells and normal blood monocytes

Research Area: Immunology, Stem Cell

Tested Application: Flow

Application: CD35 Antibody [E11] for use in flow cytometry, immunohistochemistry, western blotting, ELISA, and immunoprecipitation assays.

Specificiy: CD35

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: N/A

Clonality: Monoclonal

Clone: [E11]

Isotype: IgG1

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added

Concentration: 0.1 mg/mL

Storage Condition: Store vial at 2-8˚C

Alternate Name: CR1, complement receptor type 1, C3bR, C4bR, immune adherence receptor

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The CD35 antigen is composed of four different allotypes having different molecular weights [A (or F) - 160 kDa, B (or S) - 190 kDa, C - 220 kDa, and D - 250 kDa]. It is the receptor for C3b and is found on B cells, a subset of T cells, monocytes, neutrophils, follicular dendritic cells, erythrocytes, and kidney glomelular podocytes. CD35 mediates neutrophil and monocyte phagocytosis of particles coated with C3b and/or C4b. This interaction also enhances phagocytosis mediated by the Fc receptors.