CD38 (Cyclase) Inhibitor Screening Kit (Fluorometric) | K2102-100

CD38 (Cyclase) Inhibitor Screening Kit (Fluorometric) | K2102-100

Description: Cluster of differentiation 38 (CD38), also known as cyclic ADP ribose hydrolase or ADP-ribosyl cyclase is a multifunctional enzyme that catalyzes the synthesis and hydrolysis of Nicotinamide Adenine Dinucleotide (NAD) to Nicotinamide and ADP-ribose (ADPR). Additionally, CD38 generates second messengers, cyclic ADP-ribose using NAD as the substrate. Due to its role in NAD+ metabolism, the study of CD38 and its functions has been of great importance. It is found on the surface of many immune cells, including plasma B cells, natural killer cells, CD4+, CD8+, etc. Elevated levels of CD38 are associated with aging, obesity, diabetes, heart disease, asthma, inflammation and tumorigenesis etc. ’s CD38 (Cyclase) Inhibitor Screening Kit is a plate-based fluorometric assay designed to screen, study and characterize potential inhibitors of CD38 cyclase activity. The assay utilizes a selective CD38 substre to generate a fluorescent signal measured at Ex/Em = 300/410 nm. In the presence of potential CD38 cyclase inhibitors, the fluorescent signal is reduced. The assay is quick, easy, and sensitive for high-throughput screening of CD38 inhibitors. Additionally, the kit includes a CD38 Inhibitor as a control inhibitor.

Alternate Name: CD38 Inhibitor Screening Kit (Fluorometric) CD38 (Cyclase) Inhibitor Screening Kit

Tag Line: A plate-based fluorometric assay designed to screen, study and characterize potential inhibitors of CD38 cyclase activity.

Summary: ’s CD38 (Cyclase) Inhibitor Screening Kit is a plate-based fluorometric assay designed to screen, study and characterize potential inhibitors of CD38 cyclase activity.

Detection Method: Fluorescence (Ex/Em = 300/410 nm)

Sample Type: NULL

Species Reactivity: Mammalian

Applications: Screening or characterizing CD38 (Cyclase) inhibitors.

Features & Benefi: The assay is quick, easy, and sensitive for high-throughput screening of CD38 inhibitors. The kit includes a CD38 Inhibitor as a control inhibitor.