CD38 (Hydrolase) Inhibitor Screening Kit (Fluorometric) - K2086

K2086 | CD38 (Hydrolase) Inhibitor Screening Kit (Fluorometric) DataSheet

Cluster of differentiation 38 (CD38), also known as cyclic ADP ribose hydrolase is a type II transmembrane glycoprotein that can function either as a receptor or as an enzyme. It is found on the surface of many immune cells, including plasma B cells, natural killer cells, CD4+, CD8+ etc. It is a multifunctional enzyme involved in cell-adhesion, calcium signaling and Nicotinamide Adenine Dinucleotide (NAD+) metabolism. The hydrolase activity of CD38 helps maintain the appropriate levels of NAD+ for all NAD+ dependent metabolic processes to occur. Elevated levels of CD38 are associated with aging, obesity, diabetes, heart disease, asthma, inflammation and tumorigenesis etc. ’s CD38 (Hydrolase) Inhibitor Screening Kit is a plate-based fluorometric assay designed to screen, study and characterize potential inhibitors of CD38 hydrolase activity. The assay utilizes a selective CD38 substrate to generate a fluorescent signal measured at Ex/Em = 300/410 nm. In the presence of potential CD38 hydrolase inhibitors, the fluorescent signal is reduced. The assay is quick, easy, and sensitive for high-throughput screening of CD38 inhibitors. Additionally, the kit includes a CD38 Inhibitor as a control inhibitor.

Alternate Name : CD38 (Hydrolase) Inhibitor Screening (Fluorometric) CD38 (Hydrolase) Inhibitor Assay CD38 (Hydrolase) Inhibitor Screening Kit

Tag Line : For screening, studying and characterizing potential inhibitors of CD38 hydrolase activity

Summary : ’s CD38 (Hydrolase) Inhibitor Screening Kit is a plate-based fluorometric assay designed to screen, study and characterize potential inhibitors of CD38 hydrolase activity.

Detection Method : Fluorescence (Ex/Em = 300/410 nm)

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Applications : Screening or characterizing CD38 (Hydrolase) inhibitors.

Features and Benefits : A quick, easy, and sensitive for high-throughput screening of CD38 inhibitors. The kit includes a CD38 Inhibitor as a control inhibitor.