CD3E monoclonal Antibody | MB62740

CD3E monoclonal Antibody | MB62740 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Monkey, Dog

Application: IF, IHC, WB

Application Range: WB 1:200~4000, IHC 1:150, IF 1:100

Background: The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: CD3e molecule

Molecular Weight: 20.7 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: IMD18; T3E; TCRE

Immunogen: Full length human recombinant protein of human CD3E (NP_000724) produced in HEK293T cell.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A