CD3G polyclonal Antibody | BS90241

CD3G polyclonal Antibody | BS90241 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Application: WB IHC FC IP

Application Range: WB:1:500-1:1,000 IHC:1:50-1:200 FC:1:50-1:100 IP:1:10-1:50

Background: The T cell antigen receptor (TCR) recognizes foreign antigens and translates such recognition events into intracellular signals that elicit a change in the cell from a dormant to an activated state. Much of this signaling process can be attributed to a multisubunit complex of proteins that associates directly with the TCR. This complex has been designated CD3 (cluster of differentiation 3) . It is composed of five invariant polypeptide chains that associate to form three dimers: a heterodimer of gamma and epsilon chains (γε), a heterodimer of delta and epsilon chains (δε) and a homodimer of two zeta chains (ζζ) or a heterodimer of zeta and eta chains (ζη) . The ζ and η chains are encoded by the same gene but differ in their carboxyl-terminal ends due to an alternative splicing event. The γ, ε and δ chains each contain a single copy of a conserved immunoreceptor tyrosine-based activation motif (ITAM) .

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: CD3G polyclonal Antibody detects endogenous levels of CD3G protein.

Molecular Weight: 20 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: CD3G, T3G, CD3 gamma, CD3-GAMMA, CD3g, CD3g antigen gamma polypeptide (TiT3 complex), CD3g antigen gamma polypeptide, CD3g molecule gamma (CD3 TCR complex), CD3g molecule gamma, CD3G, FLJ17620, FLJ17664, FLJ79544, FLJ94613, MGC138597, T cell antigen receptor complex gamma subunit of T3, T-cell receptor T3 gamma chain, T-cell surface glycoprotein CD3 gamma chain, T3G,

Immunogen: Recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: Immune checkpoint signaling in the Tumor Microenvironment,Tumor-Infiltrating Immune Cell Marker Guide,