CD4 Antibody [RFT4] | 99-423

CD4 Antibody [RFT4] | 99-423 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human

Homology: N/A

Immunogen: Thymocytes and E-rosetted lymphocytes

Research Area: Immunology

Tested Application: IHC-Fr, Flow, Activity

Application: CD4 Antibody [RFT4] for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, and separation assays.

Specificiy: CD4

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: N/A

Clonality: Monoclonal

Clone: [RFT4]

Isotype: IgG1

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added

Concentration: 0.1 mg/mL

Storage Condition: Store vial at 2-8˚C

Alternate Name: T4, Leu-3

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: CD4 is a 55 kDa type I transmembrane glycoprotein and a member of the Ig-SF of cell surface receptors. It is expressed predominantly on the ���helper/inducer��� subpopulation of mature T lymphocytes and on monocytes and macrophages. Domains 1 and 2 bind to MHC Class II antigens, while domains 3 and 4 may be involved in cis interactions with the CD3/TCR complex. CD4 functions as an accessory molecule in the recognition of foreign antigens in association with MHC class II antigens by T cells.