CD40 Antibody (C-term) (Ascites) [AMM02430G]

CD40 Antibody (C-term) (Ascites) [AMM02430G] | Gentaur UK, US & Europe Distribution

Product Category: Monoclonal Antibodies

Host: Mouse

Species Reactivity: H

Specificity: This CD40 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 247-276 amino acids from the C-terminal region of human CD40.

Cellular Localisation: [Isoform I]: Cell membrane; Single-pass type I membrane protein

Molecular Weight: 30619

Clone: Monoclonal

Gene Name: CD40

Gene ID: 958

Function: Receptor for TNFSF5/CD40LG (PubMed:31331973) . Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity) .

Summary: Tissue Location: B-cells and in primary carcinomas.

Form: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:100~1600

Synonyms: Tumor necrosis factor receptor superfamily member 5, B-cell surface antigen CD40, Bp50, CD40L receptor, CDw40, CD40, CD40, TNFRSF5