Description
CD42b Antibody [MM2/174] | 99-522 | Gentaur UK, US & Europe Distribution
Host: Mouse
Reactivity: Human
Homology: N/A
Immunogen: Human plasma membrane
Research Area: Immunology, Signal Transduction
Tested Application: IHC-Fr, Flow, IP
Application: CD42b Antibody [MM2/174] for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, and immunoprecipitation assays.
Specificiy: CD42b
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: N/A
Clonality: Monoclonal
Clone: [MM2/174]
Isotype: IgG1
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Supplied in PBS
Concentration: 0.5 mg/mL
Storage Condition: Store vial at -20˚C
Alternate Name: GPIbalpha, glycocalicin
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: CD42b, also known as GPIbalpha, is a two-chain membrane glycoprotein that forms a noncovalent complex with CD42a (GPIX) on the surface of platelets and megakaryocytes. Binding of the GPIb/GPIX heterodimer to von Willebrand factor bound to exposed subendothelial surfaces is essential for platelet adhesion at sites of injury.