CD42b Antibody [MM2/174] (FITC) | 99-517

CD42b Antibody [MM2/174] (FITC) | 99-517 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human

Homology: N/A

Immunogen: Human plasma membrane

Research Area: Immunology, Signal Transduction

Tested Application: Flow

Application: CD42b Antibody [MM2/174] for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.

Specificiy: CD42b

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: N/A

Clonality: Monoclonal

Clone: [MM2/174]

Isotype: IgG1

Conjugate: FITC

Physical State: Liquid

Buffer: Supplied in PBS/NaN3

Concentration: Lot specific

Storage Condition: Store vial at 2-8˚C

Alternate Name: GPIbalpha, glycocalicin

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: CD42b, also known as GPIbalpha, is a two-chain membrane glycoprotein that forms a noncovalent complex with CD42a (GPIX) on the surface of platelets and megakaryocytes. Binding of the GPIb/GPIX heterodimer to von Willebrand factor bound to exposed subendothelial surfaces is essential for platelet adhesion at sites of injury.