CD45 Antibody [I3/2.3] | 98-781

CD45 Antibody [I3/2.3] | 98-781 | Gentaur UK, US & Europe Distribution

Host: Rat

Reactivity: Mouse

Homology: N/A

Immunogen: T1M1 (Thy-1���c) cells

Research Area: Immunology

Tested Application: E, WB, WB-NR, IHC-P, IHC-Fr, ICC, Flow, Blocking

Application: CD45 Antibody [I3/2.3] for use in flow cytometry, immunohistochemistry, and immunoprecipitation assays.

Specificiy: CD45

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: N/A

Clonality: Monoclonal

Clone: [I3/2.3]

Isotype: IgG2b

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Supplied in PBS

Concentration: 0.5 mg/mL

Storage Condition: Store vial at -20˚C

Alternate Name: LCA, leukocyte common antigen, T200, Ly-5, Receptor-type tyrosine-protein phosphatase C, Lyt-4, Ptprc

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: CD45 is the common leukocyte antigen and is expressed on all cells of hematopoietic origin except erythrocytes. CD45 exists as a number of different isoforms which result from alternative RNA splicing of exons 4, 5 and 6. The I3/2.3 monoclonal antibody recognizes a framework epitope present on all CD45 isoforms. The CD45 molecule has been implicated as playing a key role in thymic development and in antigen-driven proliferation of T cells.