CD45R Antibody [RA3-6B2] (PE-Cy7) | 98-795

CD45R Antibody [RA3-6B2] (PE-Cy7) | 98-795 | Gentaur UK, US & Europe Distribution

Host: Rat

Reactivity: Mouse, Human, Cat

Homology: N/A

Immunogen: Abelson murine leukemia virus-induced pre-B cell lymphoma

Research Area: Immunology

Tested Application: Flow

Application: CD45R Antibody [RA3-6B2] for use in flow cytometry assays.

Specificiy: CD45R

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: N/A

Clonality: Monoclonal

Clone: [RA3-6B2]

Isotype: IgG2a

Conjugate: PE-Cy7

Physical State: Liquid

Buffer: Supplied in PBS/NaN3 and a stabilizing agent

Concentration: 0.1 mg/mL

Storage Condition: Store vial at 2-8˚C

Alternate Name: B220, Ly-5, Lyt-4, Ptprc, Receptor-type tyrosine-protein phosphatase C

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: CD45R, also known as B220, a member of the protein tyrosine phosphate family and a major cell surface glycoprotein, represents a restricted form of the CD45 family which primarily recognizes only cells of B-lineage from pro-B cell through mature B lymphocytes and prior to the availability of anti-CD19 monoclonal antibodies was commonly used as a pan B-cell marker. It also reacts with certain activated T cells as well as non-MHC-restricted lytically active lymphokine-activated killer (LAK) cells. In vivo administration of RA3-6B2 has been shown to affect differentiation of both T and B cells in normal mice and reduce the level of anti-DNA antibodies and lymphadenopathies in MRL/lpr mice.