CD49b Antibody [HAS-4] (FITC) | 99-383

CD49b Antibody [HAS-4] (FITC) | 99-383 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human

Homology: N/A

Immunogen: Human keratinocytes

Research Area: Cancer, Immunology, Obesity, Signal Transduction

Tested Application: Flow

Application: CD49b Antibody [HAS-4] for use in flow cytometry and immunohistochemistry / immunocytochemistry assays.

Specificiy: CD49b

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: N/A

Clonality: Monoclonal

Clone: [HAS-4]

Isotype: IgG2a

Conjugate: FITC

Physical State: Liquid

Buffer: Supplied in PBS/NaN3

Concentration: Lot specific

Storage Condition: Store vial at 2-8˚C

Alternate Name: Integrin alpha2, VLA-2alpha, very late antigen-2

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: CD49b, a member of the integrin family of extracellular matrix and cell adhesion molecules, is the integrin alpha2 chain. CD49b associates noncovalently with CD29, the integrin beta1 subunit, to form the heterodimer integrin alpha2beta1 that binds laminin and collagen. It is expressed on B and T lymphocytes, NK cells, monocytes, platelets, fibroblasts, and long-term cultured T cells. CD49b/CD29 mediates the Mg++-dependent adhesion of platelets to collagen. It may also be utilized by fibroblasts for the reorganization of the collagen matrix during wound healing.