CD49b Antibody [HMa2] | 76-808

CD49b Antibody [HMa2] | 76-808 | Gentaur UK, US & Europe Distribution

Host: Hamster

Reactivity: mouse

Homology: N/A

Immunogen: N/A

Research Area: Immunology, Functional Assays

Tested Application: Flow, Func

Application: N/A

Specificiy: The HMa2 monoclonal antibody specifically reacts with mouse CD49b (integrin alpha 2) , a 150kDA transmembrane glycoprotein that forms the VLA-2 complex with CD29 (integrin beta 1) .

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.

Clonality: Monoclonal

Clone: HMa2

Isotype: Armenian Hamster IgG

Conjugate: Unconjugated

Physical State: liquid

Buffer: Phosphate-buffered aqueous solution, ph7.2.

Concentration: batch dependent

Storage Condition: The product should be stored undiluted at 4˚C . Do not freeze.

Alternate Name: DX5, CD49B, Itga2

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The HMa2 monoclonal antibody specifically reacts with mouse CD49b (integrin alpha 2) , a 150kDA transmembrane glycoprotein that forms the VLA-2 complex with CD29 (integrin beta 1) . VLA-2 is expressed on NK-T cells, epithelial cells, platelets, and CD+4 T lymphocytes. It is the receptor for laminin and collagen and is upregulated in response to mitogens. The Hma2 antibody is reported to partially block the interaction with collagen in T cells, but not NK cells.