CD54 Polyclonal Antibody | E-AB-13130

CD54 Polyclonal Antibody | E-AB-13130 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Antigen identified by monoclonal BB2, BB 2, BB2, CD 54, CD_antigen=CD54, CD54, Cell surface glycoprotein P3.58, Human rhinovirus receptor, ICAM 1, ICAM-1, ICAM1, ICAM1, intercellular adhesion molecule 1 (CD54), human rhinovirus receptor, Intercellular adhesion molecule 1, Major group rhinovirus receptor, MALA 2, MALA2, MyD 10, MyD10, P3.58, Surface antigen of activated B cells, BB2

Application: WB, IHC, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cardiovascular, Immunology, Stem Cells

Background: This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.

Concentration: 0.3 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human ICAM1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:25-1:100

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 58 kDa

Molecular Weight(Observed): N/A